Keywords: Tumors (Pre-Treatment), Diffusion Tensor Imaging
Motivation: Malignant tumors always metastasize along the blood or meningeal infiltration. We hope to evaluate CSF and blood changes in brain metastases patients through a simple and effective method.
Goal(s): To investigate glymphatic system and inflammation alteration in patients with brain metastases.
Approach: We combined DTI-ALPS and NLR to analyze the differences between healthy controls and patients with brain metastases.
Results: Compared with HCs, the mean ALPS index of patients with brain metastases was significantly decreased, and the NLR was significantly increased.
Impact: ALPS-index and NLR can provide a new perspective for potential assessment of how brain metastasis affects the glymphatic system and inflammatory immune system, and may also support more relevant treatments for patients.
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