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Abstract #2659

Real-time Multislice-to-volume Motion Correction with B1+ Shimming for Task-based Functional MRI at 7T

Steven Winata1, Daniel Christopher Hoinkiss2, Graeme Alexander Keith1, Sydney Nicole Williams1, Belinda Yuan Ding3, Salim al-Wasity1, Shajan Gunamony1,4, and David Andrew Porter1
1Imaging Centre of Excellence, University of Glasgow, Glasgow, Scotland, 2Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany, 3Siemens Healthineers UK, Frimley, United Kingdom, 4MR CoilTech Ltd, Glasgow, Scotland

Synopsis

Keywords: Motion Correction, Motion Correction, Brain, neuroscience, parallel transmit imaging, pTx, b1+ shimming, slice-by-slice, Siemens ICE, Terra, BrainVoyager

Motivation: 7T MRI has the capacity for higher resolution imaging, but is also more sensitive to motion artefacts and B1+ field inhomogeneity. A motion-robust, B1+ homogeneous technique will enable routine 7T usage for motion-sensitive protocols such as in fMRI.

Goal(s): Our goal was to develop integrated real-time motion correction and parallel transmission technique that improves the data quality in 7T fMRI.

Approach: The multislice-to-volume motion correction technique and the capability to execute slice-specific B1+ shims were integrated into an in-house-developed EPI sequence. A cohort was scanned in a task fMRI study.

Results: The combined technique demonstrated reduced motion, increased brain activation and improved tSNR.

Impact: With improved data quality, the integrated real-time motion correction and B1+ shimming parallel transmission technique provides an option for better statistical parametric mapping in neuroscience studies with 7T fMRI, and potentially benefiting other future 7T applications.

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Keywords