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Abstract #2672

Free-breathing self-gated 5D whole-heart CMR at 0.55T: left ventricle, right ventricle, and left atrium function analysis in a single sequence

Xavier Sieber1, Katherine Binzel2, Juliet Varghese3, Yingmin Liu2, Jérôme Yerly1,4, Ruud B. van Heeswijk1, Orlando P. Simonetti2,5, and Matthias Stuber1,4
1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, United States, 3Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, 4CIBM Center for Biomedical Imaging, Lausanne, Switzerland, 5Department of Radiology, The Ohio State University, Columbus, OH, United States

Synopsis

Keywords: Low-Field MRI, Low-Field MRI, Heart, Cardiovascular, Pulse sequence design

Motivation: CMR has not seen widespread adoption beyond large urban academic centers. The reasons for this limited uptake include the cost and time-intensive nature of CMR. 5D Free-Running CMR using self-navigation (5D CMR) implemented on a low-field clinical scanner may help bridge this gap.

Goal(s): Investigate the feasibility of cardiac function measurements using 5D CMR on a 0.55T system.

Approach: 5D CMR data were collected in 10 adult subjects and compared to results from reference 2D cines. Right- and left-ventricular ejection fraction and left atrial volume were ascertained.

Results: 5D CMR allowed for time-efficient and concordant measurements when compared to the 2D reference method.

Impact: 5D Free-Running whole-heart CMR without the need for ECG, breath-holding, navigators, or complex scan plane planning enables a highly simplified and time-efficient assessment of myocardial function on a 0.55T clinical system in under 8 min.

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