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Abstract #2680

Investigating the feasibility of resting state functional MRI with GRE EPI on a high performance 0.5 T Scanner

Arjama Halder1, Chad T. Harris2, Curtis N. Wiens2, Andrea Soddu3, and Blaine A. Chronik3
1Medical Biophysics, Western University, London, ON, Canada, 2Synaptive Medical, Toronto, ON, Canada, 3Western University, London, ON, Canada

Synopsis

Keywords: Low-Field MRI, Low-Field MRI, resting-state, functional connectivity, resting-state network, test-retest reliability

Motivation: Resting state fMRI (rs-fMRI) provides vital neurological information in acute care.

Goal(s): To demonstrate the feasibility of rs-fMRI at 0.5T.

Approach: Repeated rs-fMRI acquisitions of two healthy volunteers (n = 6, n = 4) were acquired at 0.5T using a 31 min EPI based protocol.

Results: All eleven well-established resting state networks were identified. Sensorimotor and language networks were very reliable across scans for both volunteers with intersession intra-class correlation coefficient values > 0.5.

Impact: Resting state fMRI is feasible at 0.5T with an EPI acquisition technique. The functional connectivity detected resembles a 3T database for well-established resting-state networks.

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Keywords