Keywords: MR-Guided Focused Ultrasound, Focused Ultrasound, neuromodulation
Motivation: MR-ARFI is currently used to target focused ultrasound in the brain, but as a quantitative imaging method it has the potential to provide acoustic dosimetry if the measured tissue displacement can be related back to acoustic intensity or pressure.
Goal(s): Develop a method to calculate MR-ARFI images based on high-intensity acoustic simulations of focused ultrasound and finite element modeling.
Approach: We converted acoustic beam simulations to acoustic force, which was input to an FEM solver to calculate time-resolved tissue displacements, and subsequently MR-ARFI images.
Results: The method enabled a lookup table calculation to recover acoustic intensity from MR-ARFI measurements
Impact: MR-ARFI is used to target focused ultrasound in the brain, but as a quantitative imaging method it could also provide dosimetry. We established the ability to relate simulated acoustic pressure fields to MR-ARFI images via finite element modeling.
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