Meeting Banner
Abstract #2718

Optimizing catheter based pulse application for intra-Arterial-Spin-Labeling in coronary arteries

Felix Spreter1, Simon Reiss1, Johannes Fischer1, Ali Caglar Özen1, Alexander Maier2, and Michael Bock1
1Division of Medical Physics, Dept. of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2Dept. of Cardiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Synopsis

Keywords: Interventional Devices, Interventional Devices, Arterial Spin Labeling

Motivation: Intra-Arterial-Spin Labeling (iASL) could offer an alternative for myocardial perfusion measurements without the use of contrast agents by labeling blood with a catheter transmit RF-coil.

Goal(s): To study the parameters influencing the iASL labeling efficiency inside the artery to improve the SNR.

Approach: The complex iASL process is investigated with simulations and in-vitro measurements for different coil geometries (solenoid, loop), driving currents, coil orientations relative to the magnetic field, and blood flow velocities.

Results: The simulations were in good agreement with measurements, show a maximal mean flip angle created by the labeling pulse of 105°, and a threshold behavior for the transmit current.

Impact: The improvement of the labeling process inside coronary arteries started in this study, is an important step towards making ASL a viable method for myocardial perfusion quantification.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords