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Abstract #2744

Variational Network Meets Conjugate Gradient: Inline Reconstruction and Strain Analysis of Accelerated Cardiac Cine MRI

Marc Vornehm1,2, Jens Wetzl2, Florian Fürnrohr1, Daniel Giese2,3, Rizwan Ahmad4, and Florian Knoll1
1Computational Imaging Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 2Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany, 3Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 4Biomedical Engineering, The Ohio State University, Columbus, OH, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Image Reconstruction, Strain

Motivation: Accelerated cardiac cine MRI is prone to motion artifacts and underestimation of imaging biomarkers. Furthermore, many approaches lack prospective evaluation.

Goal(s): Improve data-driven reconstruction of cardiac cine MRI and enable inline reconstruction with improved estimation of strain parameters.

Approach: Training a neural network based on a Variational Network combined with intermediate conjugate gradient optimizations and evaluation on retrospectively undersampled data. Inline integration into scanner software using the FIRE framework and prospective evaluation in terms of image quality and cardiac strain parameters.

Results: The proposed network outperformed established compressed sensing approaches both retrospectively and prospectively, and in both image quality and cardiac strain estimation.

Impact: Our research enables inline reconstruction of highly accelerated (up to real-time) cardiac cine MRI with high motion fidelity and improved strain estimation compared to well-established compressed sensing approaches.

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