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Abstract #2752

Assessment of Renal Water Exchange by T2 Selective Labeling

Narjes Jaafar1,2, Manuel Taso1,2, and David C Alsop1,2
1Beth Israel Deaconess Medical Center, Boston, MA, United States, 2Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Kidney, Kidney

Motivation: Alterations of renal water transport and exchange may reflect kidney function and disease.

Goal(s): To develop and test a novel sequence for quantitative assessment of intrarenal fluid exchange.

Approach: We developed a T2 selective labeling sequence for water exchange quantification and tested it on healthy subjects.

Results: Images showed a characteristic spatial distribution of signal with increased signal in the renal medulla, in support of its detection and assessment of fluid exchange.

Impact: Exchange imaging by T2 selective saturation may open new possibilities for the study of water transport and exchange and the diagnosis of renal disorders.

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Keywords