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Abstract #2781

Fast Joint MR T1 and T2* Parameter Mapping with Scan Specific Unsupervised Networks

Amir Heydari1, Tae Hyung Kim2, Abbas Ahmadi1, Xiaoqing Wang3,4, and Berkin Bilgic3,5
1Industrial Engineering and Management Systems, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran (Islamic Republic of), 2Hongik University, Seoul, Korea, Republic of, 3Radiology, Harvard Medical School, Boston, MA, United States, 4Boston Children’s Hospital, Boston, MA, United States, 5Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

Synopsis

Keywords: Quantitative Imaging, Image Reconstruction

Motivation: Joint MAPLE is an MR parameter mapping technique with improved results which suffers from long processing times.

Goal(s): We propose a fast version of Joint MAPLE as a self-supervised, model-based multi-parameter mapping technique capable of jointly mapping T1, T2*, frequency and proton density in a whole brain volume ~50 times faster than the original version, while retaining its parameter mapping performance.

Approach: A fast whole brain reconstruction, transfer learning and a rapid initialization in optimization is incorporated.

Results: Results show that fast Joint MAPLE retains the mapping performance of the original version and outperforms existing methods.

Impact: Fast Joint MAPLE estimates T1, T2*, frequency and proton density of a volume ~50 times faster than the original version with the same performance. A fast volume reconstruction, transfer learning and a rapid initialization is incorporated for faster mapping.

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Keywords