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Abstract #2782

Ten-fold accelerated multi-echo spiral fMRI using self-supervised physics-driven DL reconstruction

Zidan Yu1, Hongyi Gu2,3, Chi Zhang2,3, Christoph Rettenmeier1, Mehmet Akcakaya3, and V.Andrew Stenger1
1Department of Medicine, University of Hawaii, Honolulu, HI, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, fMRI

Motivation: Multi-echo fMRI holds the promise of more potential applications, however it suffers from long readout lengths.

Goal(s): Explore the possibility of using deep learning(DL) reconstruction for highly under-sampled spiral multi-echo fMRI acquisition.

Approach: Multi-echo data from four subjects were collected for DL training. Multi-echo fMRI data from another subject was used for testing the DL model. The DL model has been designed and modified to enable the reconstruction of ten-fold under-sampled fMRI images for BOLD analysis.

Results: The DL model has not only reconstructed the multi-echo spiral fMRI with good image quality, but also preserved its BOLD sensitivity with the highly under-sampled data.

Impact: With the help of DL, multi-echo fMRI may become more versatile for clinical use and future studies.

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