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Abstract #2791

Rapid High-resolution Whole-brain 3D Multi-parametric and Multi-contrast MRI with Deep Learning-based Acquisition & Reconstruction

David D Shin1, Naoyuki Takei2, Xucheng Zhu1, Fara Nikbeh1, and Suchandrima Banerjee1
1GE HealthCare, Menlo Park, CA, United States, 2GE HealthCare, Tokyo, Japan

Synopsis

Keywords: Synthetic MR, Neuro, Multi-Contrast, Data Acquisition, Machine Learning, Synthetic MR Neuro

Motivation: As the public demand for MRI grows exponentially, there is an increasing need for a one-click 3D MR exam that can generate multiple image contrasts and parametric maps as an effective way to improve patient throughput.

Goal(s): Our goal was to implement an acquisition and reconstruction method that makes high-resolution whole brain multi contrast examination possible in less than 3 minutes.

Approach: We implemented a deep learning-guided vast undersampled MR acquisition and a time efficient recon algorithm that uses a densely connected unrolled neural network.

Results: Our proposed method preserved image quality and quantitative accuracy of the multicontrast and multiparametric images.

Impact: This study demonstrates that with highly undersampled 3D QALAS acquisition combined with the DL recon algorithm, a 3-minute one-click exam is feasible that generates whole-brain high-resolution brain volumes of multiple contrasts and quantitative maps, which can enhance patient workflow in a busy clinical practice.

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Keywords