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Abstract #2795

Deep Learning with Spatio-Channel Regularization for Accelerated Cardiac Cine

Omer Burak Demirel1, Fahime Ghanbari1, Manuel A Morales1, Patrick Pierce1, Scott Johnson1, Jennifer Rodriguez1, Jordan A Street1, Warren J Manning1,2, and Reza Nezafat1
1Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, 2Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Cardiovascular

Motivation: Evaluation of cardiac function with cine imaging remains long and requires repeated breath-holds that are sometimes corrupted with artifacts if patients have non-sinus rhythm or difficulty in breath-holding.

Goal(s): To develop a deep learning method with spatio-channel regularization with multi-channel k-space reconstruction for accelerated cine imaging.

Approach: Coil-self consistency based deep learning (DL) was implemented with 3D regularization across spatial and channel dimensions in contrast to single coil-combined image used in sensitivity encoding (SENSE).

Results: Our approach at 5-fold acceleration showed quantitative improvements over SENSE-based DL on retrospectively accelerated data and showed good agreement with left ventricular (LV) measurements on prospectively accelerated data.

Impact: The spatio-channel regularized DL reconstruction shortens the scan time by a factor of 5, leading to fewer breath-holds and 2–3-minute scans. This can greatly benefit patients struggling with breath-holding and accelerate the overall scan time.

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Keywords