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Abstract #2807

Model based rEconstruction by Deep Algorithm unrolLing (MEDAL) for fast 3D whole-heart T2 mapping

Alberto Di Biase1,2, Alina Schneider3, Rene Botnar1,3,4, and Claudia Prieto1,2,3
1MILLENNIUM INSTITUTE FOR INTELLIGENT HEALTHCARE ENGINEERING, Santiago, Chile, 2School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3School of Biomedical Engineering, King’s College London, London, United Kingdom, 4Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Machine Learning/Artificial Intelligence, model-based

Motivation: T2 mapping provides quantitative myocardial tissue characterization. However, current approaches acquire several 2D contrast images which are then fitted to a model to estimate the T2 values, leading to limited coverage, and long acquisition and reconstruction times.

Goal(s): Here we propose to speed up 3D whole-heart T2 mapping using a model-based deep learning unrolling network (MEDAL) that leverages the power of machine learning and physical knowledge.

Approach: MEDAL reconstructs the T2 maps directly without reconstructing any intermediate contrast weighted images or fitting.

Results: The proposed approach was evaluated in iNAV-based free-breathing 3D T2 mapping 4x accelerated showing promising results.

Impact: A novel method for reconstructing parametric maps using a model-based deep learning unrolling network is presented. The method was demonstrated in a highly accelerated free breathing 3D whole-heart T2 mapping sequence allowing for fast and accurate T2 measurements.

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Keywords