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Abstract #2852

Investigation of Optimal Readout Frequency for the Non-Uniform B0 (NuBo) Field Cycling (FC) Scanner

Chenhao Sun1, Yonghyun Ha1, Anja Samardzija2, Heng Sun2, Ryan Gross1, Gigi Galiana1, and R. Todd Constable1
1Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States, 2Department of Biomedical Engineering, Yale University, New Haven, CT, United States

Synopsis

Keywords: Low-Field MRI, Low-Field MRI

Motivation: The field cycling (FC) scanner introduces an extra degree of freedom for adjusting the B0 field strength during both polarization and readout. However, the ideal readout Larmor frequency remains unexplored.

Goal(s): To investigate the optimal readout Larmor frequency for the non-uniform B0 (NuBo) scanner regarding SNR, T2*, and T2 dephasing.

Approach: Controlled experiments at two Larmor frequencies, 1MHz and 2MHz, were conducted. Echo trains at these two frequencies were acquired.

Results: Results show that readout at a lower Larmor frequency could benefit from a longer echo train, and longer T2*, but with the penalty of a smaller initial signal amplitude.

Impact: This research conducted a comparison of the trade-off between SNR, T2* and T2 decay across various readout Larmor frequencies, potentially offering insights for researchers in the field of field cycling in the future.

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