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Abstract #2893

Diagnostic value of modified clear cell likelihood score based on pseudocapsule for predicting the malignancy in small renal masses

Yu-Wei Hao1,2, Xu Bai1, Meng-Qiu Cui1, Xue-Yi Ning1, Xiao-Hui Ding3, Hui-Yi Ye1, and Hai-Yi Wang1
1Department of Radiology, First Medical Center, Chinese PLA General Hospital, Beijing, China, 2Department of Radiology, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China, 3Department of Pathology, First Medical Center, Chinese PLA General Hospital, Beijing, China

Synopsis

Keywords: Kidney, Kidney, Multi-parameter magnetic resonance imaging; Clear cell likelihood score; Clear cell renal cell carcinoma; Pseudocapsule

Motivation: Clear cell likelihood score version 2.0 (ccLS v2.0) is not yet able to predict malignancy in small renal masses (SRMs). Pseudocapsule may provide added value with ccLS v2.0

Goal(s): To develop a modified clear cell likelihood score based on pseudocapsule (m-ccLS) for predicting malignancy in SRMs

Approach: Receiver operating characteristic curve (ROC), net reclassification index (NRI), and integrated discrimination improvement (IDI) were used to compare diagnostic value of m-ccLS and ccLS v2.0

Results: Area under curve (AUC), NRI and IDI of m-ccLS were superior to those of ccLS v2.0 for the diagnosis of malignancy. The likelihood of malignancy increased with higher m-ccLS scores

Impact: M-ccLS achieved predict malignancy of small renal masses (SRMs). M-ccLS may be a valuable tool for expanding the clinical application of this scoring system and contributing to its further promotion and dissemination

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