Abstract #2970

Volume isotropic 3D myelin weighted Imaging using broadband IR-prepared FLORET UTE: comparison with myelin water fraction

Minako Azuma¹, Masahiro Enzaki², Masami Yoneyama³, Ryan Robison⁴, Yoshihito Kadota¹, and Kengo Matsumura¹

¹Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan, ²Division of Radiology, Miyazaki University Hospital, Miyazaki, Japan, ³Philips Japan, Tokyo, Japan, ⁴Philips Healthcare, Rochester, MN, United States

Synopsis

Keywords: Multiple Sclerosis, Neurodegeneration

Motivation: Myelin water fraction (MWF) is a promising method for quantitative evaluation of myelin in the brain. FLORET MR bone imaging using UTE sequences has possibility to show brain myelin structure because myelin also has quite short T2 relaxation times.

Goal(s): To demonstrate the feasibility of FLORET MyelinVIEW in comparison with MWF.

Approach: We evaluated the FLORET MyelinVIEW and MWF based on the distribution of myelin in the brain structures.

Results: FLORET MyelinVIEW may be useful for evaluating the distribution of myelin.

Impact: FLORET MyelinVIEW showed comparable distribution of brain myelin to MWF, it may be useful to visualize the myelin distribution with the 3D isotropic images.

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