Keywords: Segmentation, Spectroscopy, Point Resolved Spectroscopy, PRESS
Motivation: Rapid Relaxometry through Acquisition of Multiple Saturated T2 Curves (RRAMSC) is a time-efficient STEAM compartmental analysis method. While it has been theorized that the technique can also be used in PRESS localization, it has not yet been demonstrated.
Goal(s): Our goal is to examine RRAMSC for separating the tissue water and CSF when using PRESS localized spectroscopy.
Approach: To our knowledge, this is the first study to demonstrate the applicability of RRAMSC for PRESS in vivo.
Results: Results show excellent agreement between theoretical and actual differences for a PRESS-based RRAMSC, showing negligible differences and a mean error of less than 2%
Impact: This study extends the rapid relaxometry through acquistion of multiple saturated T2 curves, a time-efficient relaxometry technique for water compartmentalization, to the more commonly used point resolved spectroscopy localization technique.
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