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Abstract #3003

A new approach for reproducible water fraction and T1 mapping across different qMRI acquisition protocols

Eden Mama1, José P. Marques2, and Aviv A. Mezer3
1The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel, 2Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, Netherlands, 3The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel

Synopsis

Keywords: Data Processing, Brain

Motivation: The quantitative MRI community uses various acquisition approaches to extract the same quantitative maps while continuously working to find the agreement between them.

Goal(s): Our goal was to examine the agreement between the outcomes of two acquisition approaches, variable flip angle and MP2RAGE.

Approach: We produced a postprocessing method that generated qMRI maps from both acquisition approaches and controlled the similarities between the maps.

Results: Our new approach produced strong correlations between qMRI maps acquired with different sequences, emphasizing the agreement and consistency between them.

Impact: Our approach provides high agreement between different qMRI acquisition strategies, that may allow harmonization between different scanners and MR protocols and enable the usage of multiple datasets for research purposes.

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