Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas), B1 correction, B0 correction
Motivation: B0 and B1 inhomogeneities affect signal quantification and kinetic modelling but are challenging to map and correct for in hyperpolarized MRI due to the signal being exogenous and non-renewable.
Goal(s): Develop a fully-integrated B0 and B1 mapping method that does not require specialized pulse sequence programming, additional hardware, nor any additional carbon-13 dose.
Approach: Varying echo times and flip angles in the imaging sequence.
Results: The in-vivo field maps agreed well with independently acquired maps and could correct for B0 off-resonance blurring and B1 inhomogeneity.
Impact: A fully-integrated B0 and B1 mapping and correction method for hyperpolarized carbon-13 MRI is presented and validated in vivo. This method is readily implemented and can improve image quality, helping 13C metabolic imaging become more robust for clinical studies.
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