Keywords: Non-Proton, Non-Proton
Motivation: Sodium MRI (23Na-MRI) holds significant potential, but its clinical use is still limited due to challenges arising from low signal-to-noise ratio (SNR). Balanced steady-state free precession (bSSFP) sequences are particularly suited for 23Na-MRI, being highly SNR efficient, but there are opportunities to extract more signal components.
Goal(s): We aim to improve SNR in sodium bSSFP acquisitions and produce additional tissue contrasts.
Approach: We propose a strategy to extract additional information from a series of phase-cycled bSSFP images using different linear combinations.
Results: Three different signal components were extracted from phase-cycled bSSFP data and combined. Results showed an SNR boost in fluid.
Impact: This offers a simple way to improve the SNR in sodium MRI images, with potential applications being pathologies that alter biofluid sodium concentrations.
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