Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas), Coronary Artery Disease, FDG PET-CT, Ischemic Heart Disease
Motivation: Coronary Artery Disease (CAD) continues to be a significant health issue worldwide, necessitating enhanced diagnostic methods capable of imaging cardiac metabolism. Hyperpolarized Carbon-13 Magnetic Resonance Imaging (HP-13C MRI) offers a potential solution for the non-invasive evaluation of metabolism in the human heart.
Goal(s): Our goal is to demonstrate the feasibility of HP-13C MRI in two human subjects with advanced CAD.
Approach: By examining these subjects, we have successfully imaged metabolic abnormalities within the myocardium.
Results: Our results indicate promising potential for using this technology to visualize dynamic changes in cardiac energetics associated with CAD. These findings can potentially influence the management of CAD.
Impact: This study establishes HP 13C-MRI as a safe, non-invasive tool for visualizing metabolic abnormalities in CAD patients, paving the way for more precise management of ischemic heart disease and prompting further comparative research with traditional imaging methods.
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