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Abstract #3088

Predicting Postoperative Outcomes in MRI-Negative Refractory Temporal Lobe Epilepsy Patients Using Dynamic Regional Homogeneity

jie hu1 and jie lu1
1Department of Radiology, Xuanwu Hospital, Capital Medical University, beijing, China

Synopsis

Keywords: Epilepsy, Epilepsy

Motivation: This study is motivated by the need for better predictive indexs for postoperative outcomes in MRI-negative refractory temporal lobe epilepsy (TLE) patients.

Goal(s): To ascertain whether machine learning models using dynamic regional homogeneity (dReHo) can predict surgical success in these patients.

Approach: The approach involved analyzing resting-state fMRI data from TLE patients and healthy controls, calculating ReHo and dReHo values, and applying these as features in a support vector machine classifier.

Results: The classifier using dReHo achieved 73.3% accuracy in predicting postoperative outcomes, significantly outperforming the ReHo-based model.

Impact: The ability to predict postoperative outcomes using dReHo could guide clinical decision-making and patient counseling, potentially leading to improved management of TLE.

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