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Abstract #3105

Subtype classification of Functional Pituitary Adenomas based on MRI Radiomics.

Elizabeth Nailoke Ndimulunde1, Bing-Fong Lin1, Chia-Feng Lu1, and Dao-Chen Lin2
1Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, 2Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan

Synopsis

Keywords: Radiomics, Radiomics

Motivation: Pituitary adenomas (PAs) are a rare but clinically diverse group of tumors with varying hormone secretion profiles and clinical characteristics, comprising 15% of intracranial tumors. Typical classification of PAs relies on blood hormone levels as gold standard test, with a limited exploration into assessing hormone status using neuroimaging biomarkers.

Goal(s): We aim to offer a practical MRI-based classification model, improving clinical PA management.

Approach: Our study developed a machine learning model using MRI radiomics as image biomarkers for the classification of PAs focusing on six subtypes.

Results: Our SVM model showed an accuracy of 0.65 based on MRI images.

Impact: Our radiomics classification model promises to revolutionize MRI PA classification and diagnosis, enhancing clinical management and benefiting scientists, clinicians, and patients by enabling more accurate and efficient diagnostics and treatments.

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Keywords