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Abstract #3205

Noninvasive Early Detection and Stage of Chronic Lung Diseases with Precision MRI (pMRI)

Dongjun Li1, Zongxiang Gui1, Jingjuan Qiao1, Sophia Bamishaye1, and Jenny Yang2
1Georgia State University, Atlanta, GA, United States, 2Chemistry, Georgia State University, Atlanta, GA, United States

Synopsis

Keywords: Contrast Agents, Lung, MRI, collagen, Protein-based contrast agent, lung fibrosis, IPF, COPD, lung cancer

Motivation: MRI diagnosis of lung has a limitation due to the air in the lungs which prevents the water signals. We use precision MRI to image the small lesions or fibrosis in the lung.

Goal(s): Our goal is to quantitatively stage the lung diseases by MRI contrast agents.

Approach: Our novel MRI contrast agent is biomarker specific which enables it target to the lung lesions or fibrosis.

Results: We are able to image the lung cancer and metastasis as well as lung fibrosis using our developed MRI contrast agent.

Impact: The imaging of lung tumor lesion or fibrosis is always hindered by the lung features. Our novol contrast agents enable us to image the lung diseases at early stages.

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Keywords