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Abstract #3229

Machine Learning-Based Lateralization of Mesial Temporal Lobe Epilpepsy Using ASL MRI

Hossein Rahimzadeh1, Mohammad-Reza Nazem-Zadeh2, Hadi Kamkar3, and Seyed Alireza Khanghahi3
1Department of Biomedical Engineering and Medical Physics, Shahid Beheshti University of Medical Sciences, Tehran, Iran (Islamic Republic of), 2Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), 3Department of Biophysics, Faculty of Biological Sciences,, Tarbiat Modares University, Tehran, Iran (Islamic Republic of)

Synopsis

Keywords: Epilepsy, Perfusion, ASL, CBF . mTLE, Machin learning

Motivation: Utilizing perfusion features to differentiate left and right mesial temporal lobe epilepsy (mTLE) using machine learning.

Goal(s): The study aims to assess ASL MRI's perfusion analysis ability to identify abnormalities in brain regions for distinguishing between mTLE cases and normal cohorts.

Approach: Cerebral blood flow obtained features used by different machine learning classifiers to separate right and left mTLE form control cohort.

Results: The utilization of CBF features proved valuable and effective in the machine learning-based classification of right and left mTLE data from the control cohort.

Impact: This study's outcomes benefit medical professionals and drug-resistant mTLE patients by expediting surgical assessments and enhancing treatment outcomes through improved lateralization and epilepsy classification.

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