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Abstract #3237

Practical sampling strategies for volumetric cardiac real-time MRI using stack-of-spirals at 0.55T

Prakash Kumar1, Rajiv Ramasawmy2, Ahsan Javed2, Ye Tian1, Adrienne Campbell-Washburn2, and Krishna S. Nayak1
1Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States, 2Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Synopsis

Keywords: Data Acquisition, Data Acquisition, Low-field MRI, Acquisition Methods, Cardiovascular

Motivation: Volumetric real-time MRI is desirable to accurately characterize beat-to-beat cardiac function in patients with arrythmia or heart failure.

Goal(s): To identify practical data sampling strategies for volumetric real-time MRI and evaluate cardiac volume measurements against gated reference scans.

Approach: We focus on stack-of-spirals bSSFP at 0.55T. We use simulations and in-vivo experiments to compare three sampling strategies that minimize eddy currents.

Results: A Gaussian distribution of the stack-of-spirals was found to provide the best real-time image quality and most accurate LV volumes, with under-estimation of end-diastolic volume by 7.44% and over-estimation of end-systolic volume by 18.33%.

Impact: Beat-to-beat cardiac function is important to measure in the context of arrhythmia, cardiac stress testing and in interventional MRI, where real-time volumetric coverage will facilitate assessment and monitoring of cardiac function.

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Keywords