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Abstract #3242

A novel sequence for Simultaneous imaging of cerebral Arteries and VEins (SAVE) based on velocity-selective arterial spin labeling

Lixin Liu1, Lili Wang1, Ying Hua Chu2, Jian Wang3, Hao Li1,4, He Wang1,4,5, and Zhensen Chen1,4
1Institute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, China, 2MR Research Collaboration Team, Siemens Healthineers Ltd., Shanghai, China, 3The Department of Neurosurgery, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou, China, 4Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence (Fudan University), Ministry of Education, Shanghai, China, 5Human Phenome Institute, Fudan University, Shanghai, China

Synopsis

Keywords: Data Acquisition, Vessels

Motivation: The conventional velocity-selective ASL-based (VSASL) MRA couldn’t separate arteries and veins unless additional module is used, which would cause long scan time. In addition, its acquisition efficiency is low since a long waiting time for blood refreshing.

Goal(s): To proposed a VSASL-based sequence for Simultaneous imaging of cerebral Arteries and VEins (SAVE).

Approach: SAVE uses the waiting period between consecutive shots of VSASL MRA to acquire SWI data. VSASL MRA/MRV were obtained by subtracting Control images from Label images, while SWI images were averaged to increase SNR.

Results: SAVE-VSASL MRA/MRV can well depict arteries and veins, and SAVE-SWI MRV could depict veins well.

Impact: The novel sequence can obtain decent VSASL MRA/MRV and SWI MRV images. The combination of the VSASL MRA/MRV and SWI MRV in SAVE should allows separation of arteries and veins by post-processing, that may be useful in clinical settings.

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Keywords