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Abstract #3267

Quantitative and Qualitative Evaluation of Geometric Distortion Correction in Submillimetre fMRI for Accurate Functional Mapping at 7T

Seong Dae Yun1 and N. Jon Shah1,2,3,4
1Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Juelich, Juelich, Germany, 2Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Juelich, Juelich, Germany, 3JARA - BRAIN - Translational Medicine, Aachen, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Germany

Synopsis

Keywords: Data Processing, Data Analysis, Geometric Distortion Correction, EPI, fMRI, Functional Mapping Accuracy, Submillimetre resolution, and Ultra-high field

Motivation: Distortion correction in EPI has been utilised in numerous fMRI studies. However, the impact of the distortion correction on submillimetre fMRI analysis remains largely unexplored.

Goal(s): This work performs quantitative and qualitative evaluation of geometric distortion correction with various criteria in submillimetre fMRI at 7T.

Approach: Submillimetre EPI (0.73 × 0.73 mm2) was employed for visual fMRI, and the distortion-corrected data were evaluated in terms of spatial resolution, functional mapping accuracy, and histogram distribution.

Results: This work demonstrates the effectiveness of distortion correction in submillimetre fMRI, revealing substantially enhanced mapping accuracy without significant deterioration in spatial resolution or functional activation distribution.

Impact: The quantitative and qualitative evaluation of EPI distortion correction presented in our work demonstrates the effectiveness of distortion correction in submillimetre fMRI at 7T, revealing substantially enhanced mapping accuracy without a significant deterioration in spatial resolution or functional activation distribution.

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Keywords