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Abstract #3278

Enhanced neural activity detection in the fMRI using polar Fourier transform

Babak Feizifar1, Sina Ghaffarzadeh2, Faeze Makhsousi1, Vahid Ghodrati2, and Abbas Nasiraei-Moghaddam3
1Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (Islamic Republic of), 2Institute for Research in Fundamental Sciences (IPM), Tehran, Iran (Islamic Republic of), 3Amirkabir University of Technology, Tehran, Iran (Islamic Republic of)

Synopsis

Keywords: fMRI Analysis, fMRI

Motivation: Alternative distortion-reducing methods are needed since NUFFT reconstruction of modestly undersampled radial k-space creates streaking artifacts that influence the entire image and fMRI study's ROI.

Goal(s): Our objective is to demonstrate that the ROI in our fMRI study is less exposed to aliasing artifacts when PFT reconstruction is used as opposed to NUFFT reconstruction.

Approach: Radial-based fMRI images with 2x undersampling were reconstructed using PFT. The neural activity map was then compared to NUFFT-based reconstruction.

Results: Compared to the NUFFT, our proposed approach achieved a qualitatively and quantitatively improved activation map thanks to the distinct artifact characteristic of the PFT.

Impact: Global streaking artifacts in reconstructed images from undersampled radial k-space may seriously affect fMRI study ROI and lead to incorrect brain activity maps. This work used the PFT approach to reduce ROI aliasing artifact in fMRI studies.

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Keywords