Keywords: New Trajectories & Spatial Encoding Methods, Spectroscopy, Ultra high field
Motivation: Cardiac 31P MRS allows the probing of metabolism in various heart diseases, however, commonly employed 3D MRSI techniques are slow even at 7 T.
Goal(s): Our work aims to evaluate the use of compartment-based localised spectroscopy using a linear algebraic model (SLAM).
Approach: 31P MRSI data was collected using concentric ring trajectory acquisitions and SLAM was used to reconstruct 31P signal from the myocardium.
Results: We show increased SNR and reduced uncertainty in determining the cardiac PCr signal, in addition to also reducing the repeatability of PCr/ATP ratio measurements when compared to a 2.5 minute, NUFFT-reconstructed CRT protocol.
Impact: Repeatable and high-SNR 31P acquisitions will allow the probing of cardiac energetics in patient populations that were previously unable to attend prolonged scan sessions at ultra-high field strengths.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords