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Abstract #3294

Rapid gradient-recalled echo line scanning with crisp line profiles for human MRI at 7 Tesla

Martijn A Cloos1, Shota Hodono1, Mukund Balasubramanian2, and Jonathan R Polimeni2,3,4
1Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, Australia, 2Department of Radiology, Harvard Medical School, Boston, MA, United States, 33Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 4Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Synopsis

Keywords: New Signal Preparation Schemes, Pulse Sequence Design, Line Scanning

Motivation: Line-scanning trades coverage for speed and resolution in a single direction, suitable for the study of mesoscale structure and functional dynamics across cortical depth. However, at ultra high-field strength, the sampling rate is constrained by the specific absorption rate.

Goal(s): Facilitate Rapid gradient-recalled echo line scanning with crisp line profiles for human MRI at 7 Tesla.

Approach: A new line-scan Tip-Down Tip-Up based preparation module.

Results: Using the proposed preparation module, it is possible to perform gradient-recalled echo line scanning experiments with short TR and crisp line profiles.

Impact: Using the proposed preparation module, it is possible to perform gradient-recalled echo line scanning experiments with short TR and crisp line profiles. Such advances can be used to study functional dynamics across cortical depth with high sampling rates.

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