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Abstract #3305

Silent Looping Star fMRI with enhanced Encoding and Reconstruction Performance

Ana Beatriz Solana1,2, Brice Fernandez3, Nikou L Damestani2, Tobias C Wood2, Steven CR Williams2, and Florian Wiesinger1,2
1GE HealthCare, Munich, Germany, 2King's College London, London, United Kingdom, 3GE HealthCare, Buc, France

Synopsis

Keywords: fMRI Acquisition, fMRI, silent, Looping Star, pulse sequence design, non-cartesian reconstruction

Motivation: Silent Looping Star fMRI offers unique advantages for neuroscience investigation, but image quality is affected by undersampling artifacts.

Goal(s): Here, we describe novel methods for improving the spatiotemporal encoding efficiency of Looping Star and thereby further advance its utility for silent fMRI.

Approach: A new Looping Star encoding scheme which adds extra out-of-plane oscillations and thereby improves overall encoding efficiency is introduced and combined with auto-calibrated cgSENSE parallel imaging reconstruction.

Results: The sharpest, most intensity uniform images and lowest background noise are demonstrated by the combination of both enhancements while maintaining BOLD sensitivity in a simultaneous, combined visual and auditory fMRI task.

Impact: The combination of a new trajectory and auto-calibrated parallel imaging leads to sharper and more uniform silent fMRI images with reduced streaking artifacts as demonstrated visually and on a visual-auditory fMRI task.

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Keywords