Keywords: Neurotransmission, fMRI (resting state)
Motivation: To leverage the intrinsic multi-echo capabilities of Looping Star (ME-LS) for fMRI applications to minimize susceptibility-related signal loss to enhance sensitivity to underlying neurovascular changes.
Goal(s): Our objective is to demonstrate feasibility of detecting resting state networks using a silent multi-echo fMRI approach enabled by Looping Star
Approach: Resting-state Multi-echo Looping Star fMRI was implemented on MAGNUS and scanned in healthy volunteers.
Results: This feasibility study shows established resting-state networks and connectome matrixes for multi-echo Looping Star fMRI and highlights the impact of the broad parameter space accessible with MAGNUS for Looping Star.
Impact: Silent ME-fMRI has a multitude of advantages, ranging from increased sensitivity to neuro-correlates of sleep dysregulation, auditory-sensory studies, neurological disorders and to provide a more immersive experience by combining sound with visual stimuli in the MR environment.
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