Keywords: fMRI Acquisition, fMRI (task based), diffusion
Motivation: Addressing the uncertainty of dfMRI's spatial specificity compared to BOLD-fMRI, considering the influence of perfusion and potential for more localized brain activation mapping.
Goal(s): To evaluate whether six-directional MPG dfMRI enhances the localization of brain activity in response to visual stimulation versus standard BOLD-fMRI.
Approach: Employed high-resolution 7T MRI with dfMRI and BOLD protocols, analyzing data with advanced pre-processing and statistical methods to compare spatial activation patterns.
Results: dfMRI demonstrated more confined activation regions, especially at higher b-values, suggesting improved spatial specificity, although complete isolation from BOLD-fMRI's T2* changes remains challenging.
Impact: Enhanced dfMRI specificity could refine our understanding of neural activity patterns, crucial for advancing cognitive neuroscience and developing targeted brain-based interventions.
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