Keywords: Vascular, Blood vessels, vessels; TOF; Angiography
Motivation: Clinicians express concerns about false-positive findings, leading to uncertainties in the reliable interpretation of TOF-MRA.
Goal(s): This study focuses on improving the reliability of TOF-MRA for cerebrovascular imaging.
Approach: By incorporating a small flip-angle spatially-selective fat-suppression and utilizing the shortest echo-time, signal loss is minimized, and uniform fat-suppression is achieved.
Results: The results, compared to conventional protocols, demonstrate superior quality and reliability by reducing spin-dephasing and achieving uniform fat-suppression without compromising blood signal quality or requiring extensive post-processing. This approach effectively mitigates the risk of false-positive findings and overestimation of stenosis, potentially establishing it as a more effective routine clinical examination for MRA.
Impact: By improving the reliability of TOF-MRA through optimized fat-suppression and echo-time reduction, it enhances the accuracy of evaluating cerebrovascular abnormalities. This advancement enables clinicians to have greater confidence in interpreting TOF-MRA images and reduces the risk of false-positive findings.
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