Keywords: Vessel Wall, Vessels, GRASP, MRA
Motivation: The mortality and disability rates following cerebral aneurysm rupture remain significantly high. Recently, pulsation of aneurysms has been suggested as a novel risk factor of rupture.
Goal(s): To harness the ultra-high temporal resolution and signal-to-noise ratio of the modified GRASP technique with 7T MRI to visualize pulsatile motions of cerebral aneurysms.
Approach: A pulsatile aneurysm phantom and aneurysm patient were scanned using a 3D-cine MRI technique, aiming to capture dynamic aneurysmal wall movements at high spatial and ultra-high temporal resolution.
Results: The new imaging technique successfully depicted pulsatile movements in the aneurysm phantom and subject, suggesting a novel predictor for aneurysm rupture.
Impact: This study presents a 3D-cine MRI method at 7T, capturing aneurysm pulsations with ultra-high frame rates in the tens of milliseconds range, promising to refine rupture risk assessments and potentially reducing adverse outcomes in cerebral aneurysm management.
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