Keywords: Vascular, Cardiovascular, coronary
Motivation: Coronary magnetic resonance angiography (MRA) has not been widely used due to lower diagnostic accuracy. The combination of diastole and systole imaging may enhance its clinical applications.
Goal(s): Designing a coronary MRA protocol combining diastole and systole imaging and evaluating its diagnostic performance for detecting significant coronary artery disease (CAD).
Approach: 3.0-T non-contrast coronary MRA was carried out twice at diastole and systole. Significant CAD was evaluated by coronary MRA as follows:1) by diastole mode, 2) by systole mode, and 3) by combined mode.
Results: Combined coronary MRA showed equally high sensitivity but improved specificity than single diastolic mode.
Impact: This study demonstrated that 1) 3.0-T non-contrast coronary MRA using combinational diastole and systole imaging can noninvasively detect CAD with high sensitivity and moderate specificity; 2) Combining diastole and systole imaging improved the diagnostic accuracy of coronary MRA, especially specificity.
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