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Abstract #3394

Slice-to-Volume 4D flow MRI in pediatric patients with congenital heart disease

Datta Singh Goolaub1, Valerie Beland1,2, Sharon Portnoy1, Shi-Joon Yoo3, Christopher Z Lam3, and Christopher K. Macgowan1,2
1Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 2Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada

Synopsis

Keywords: Cardiovascular, Pediatric, Multidimensional Flow Imaging

Motivation: In the absence of injected contrast agent, the quality of magnitude data from traditional 4D flow techniques can be poor, making structural visualization and blood vessel segmentation challenging.

Goal(s): Slice-to-volume 4D flow data has inherently high signal in blood vessels owing to in-flow effects. We apply slice-to-volume 4D flow in pediatric patients and evaluate its accuracy.

Approach: 7 pediatric patients were imaged with slice-to-volume 4D flow. Dynamic magnitude reconstructions and angiograms were assessed. The flow accuracy was evaluated using traditional 2D phase contrast MRI.

Results: Slice-to-volume 4D flow provided accurate flow quantification along with high quality anatomical and angiographic visualisations without contrast injection.

Impact: Volumetric flow imaging was performed using slice-to-volume 4D flow in pediatric patients. The technique provided accurate flow quantification along with high quality anatomical and angiographic visualisations without contrast injection.

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Keywords