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Abstract #3452

Visualization framework for voxel-wise adjacency matrices for graph-theorical based analysis methods on fMRI data

Yanlu Wang1,2 and Tie-Qiang Li2,3
1Oncology-Pathology, Karolinska Institute, Stockholm, Sweden, 2Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden, 3Clinical Sciences, Intervention and Technology, Karolinska Institute, Stockholm, Sweden

Synopsis

Keywords: fMRI Analysis, Visualization

Motivation: Graph-theoretical methods to analyze fMRI data can be powerful and flexible. Common to such methods is the construction of a graph adjacency matrix, which cannot be intuitively understood when visualized in itself.

Goal(s): We aim to develop a framework to visualize adjacency matrices intuitively while retaining intuitive spatial localizability in relation to the brain.

Approach: By stratify voxel-wise functional connectivity adjacency matrices through agglomerative clustering to form edge bundles, we 3D-render them with their end-point locations in a brain contour to ease localization.

Results: 3D rendered, color-coded, edge bundles and their end-points can be distinctly identified in relationship to the brain.

Impact: Our visualization framework allows both scientist and clinicians to employ graph theoretical analysis methods on fMRI data in a intuitive manner while retaining spatial localizability in the brain.

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