Abstract #3499

Point spread function(PSF) encoding EPI versus BLADE DWI in brain tumor diagnosis

Wen Zhong¹, Yuan Lian¹, Zhimin Huang², Mangsuo Zhao², Kun Zhou³, Xianchang Zhang⁴, Dehe Weng³, Yishi Wang⁴, Yue Yang^1,5, Yuqi Zhang², and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Department of Neurosurgery，Yuquan Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China, ³Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ⁴MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China, ⁵Department of Mathematics and Statistics, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, United States

Synopsis

Keywords: Diffusion Acquisition, Diffusion Tensor Imaging

Motivation: High-resolution DWI plays a crucial role in brain tumor diagnosis. Previous studies have introduced two high-resolution distortion-free DWI techniques: PSF and BLADE. However, no one has yet compared the two in brain MR imaging.

Goal(s): To compare the image quality of PSF and BLADE in high-resolution DWI.

Approach: In this study, scan parameters were adjusted to achieve the optimized image quality for PSF and BLADE. Subsequently, scans were performed on patients, and the final image quality was compared.

Results: With scanning times being similar, PSF exhibits a superior SNR compared to BLADE while its performance is suboptimal at the boundaries of brain tissues.

Impact: A preliminary comparison of the image quality between PSF and BLADE has been conducted, paving the way for more in-depth clinical research in areas such as diagnostic accuracy and imaging quality control.

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