Abstract #3517
Prostate MRI at 7T using high-performance gradients and an 8Tx/16Rx RF array: a clinical feasibility study
Daniel Wenz1,2, Thomas De Perrot3, Ibtisam Aslam3, Gian Franco Piredda4,5,6, Roberto Martuzzi6, Loan Mattera7, Jean-Francois Deux3, Pierre-Alexandre Poletti3, Carl Glessgen3, Antoine Delattre-Klauser4,5,6, Tom Hilbert4,8,9, Sebastian Schmitter10, Saskia Wildenberg11,12, Andreas Bitz12, Armin Michael Nagel11, Nico Egger11, Sophia Nagelstrasser11, Titus Lanz13, Ralph Kimmlingen14, Juergen Herrler14, Massimo Valerio15, Lijing Xin1,2, and Jean-Paul Vallee3
1CIBM Center for Biomedical Imaging, Lausanne, Switzerland, 2Animal Imaging and Technology, EPFL, Lausanne, Switzerland, 3Division of Radiology, Geneva University Hospital and University of Geneva, Geneva, Switzerland, 4Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 5CIBM Center for Biomedical Imaging, Geneva, Switzerland, 6Human Neuroscience Platform, Fondation Campus Biotech Geneva, Geneva, Switzerland, 7Fondation Campus Biotech Geneva, Geneva, Switzerland, 8Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 9LTS5, EPFL, Lausanne, Switzerland, 10Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 11Institute of Radiology, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 12Electrical Engineering and Information Technology, University of Applied Sciences – FH Aachen, Aachen, Germany, 13Rapid Biomedical, Rimpair, Germany, 14Siemens Healthineers, Erlangen, Germany, 15Division of Urology, Geneva University Hospital and University of Geneva, Geneva, Switzerland
Synopsis
Keywords: Prostate, Prostate, High-field MRI
Motivation: To better detect and delineate prostate cancer using ultrahigh field MRI.
Goal(s): To investigate if clinical prostate MRI at 7T using recent technological advances is feasible.
Approach: Prostate MRI was performed in 5 healthy volunteers using the latest generation of whole-body 7T MRI scanners incorporating enhanced gradient performance, advanced deep learning based image reconstruction and an 8Tx/16Rx torso array.
Results: High image quality with an unprecedented spatial resolution and a sharpness obtained at 7T outperformed those obtained at 3T even when time-matched sequences were acquired.
Impact: The preliminary data obtained from several volunteers provides a great encouragement to start clinical studies in prostate cancer patients.
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