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Abstract #3518

Annotation of Benign Prostatic Hyperplasia Lesions Can Improve the Detection of Prostate Cancer

Yinqiao Yi1, Zhenwei Ding2, Guoquan Huang2, Dongmei Wu1, Yang Song3, and Guang Yang1
1Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, shanghai, China, 2Department of Medical Imaging, the Second People's Hospital of Wuhu, Wuhu, Anhui Province, China, 3Siemens Healthineers Ltd., shanghai, China

Synopsis

Keywords: Prostate, Prostate, BPH, PCa

Motivation: Accurate interpretation of prostate MRI demands a high level of expertise and deep learning models for prostate cancer (PCa) detection often suffer from low specificity.

Goal(s): To explore the value of annotation of benign prostatic hyperplasia (BPH) to prostate cancer (PCa) detection.

Approach: We retrospectively collected 96 patients with PCa and 92 patients with BPH, all scanned with PI-RADS protocol. Two deep learning models were built: Model1 only detected PCa while Model2 simultaneously detected BPH and PCa.

Results: Model2 achieved superb performance with test AUC of 0.995, outperforming Model1 whose test AUC was 0.770.

Impact: Explicitly using the BPH label improved the performance of PCa detection significantly, implying multi-task deep learning models targeting multiple diseases are not only more in line with the needs of clinical applications, but can also bring about performance improvement.

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