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Abstract #3533

Differentiation of cardiac inflammatory diseases by myocardial cine T2 mapping

Mana Kato1, Michinobu Nagao1, Masami Yoneyama2, Yasuhiro Goto1, Isao Shiina1, Kazuo Kodaira1, and Shuji Sakai1
1Tokyo Women's Medical University, Tokyo, Japan, 2Philips Japan, Tokyo, Japan

Synopsis

Keywords: Inflammation, Infiltration, Cardiomyopathy

Motivation: Development of a non-contrast differential method for cardiac inflammatory disease

Goal(s): Accurate identification of cardiac sarcoidosis and myocarditis

Approach: Cardiac cine imaging to project T2 values using T2prep-based T2 mapping with dynamic multiple trigger-delay framework

Results: Diastolic cine T2 values (54.2msec.) discriminated cardiac sarcoidosis from myocarditis with an AUC of 0.879, sensitivity of 86%, and specificity of 77%.

Impact: This method is a new technique that captures changes in myocardial properties during the cardiac cycle without the use of contrast media.

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Keywords