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Abstract #3554

Evaluating 0.55T FISP MRF using EPG-X Formalism

Zhibo Zhu1 and Krishna S. Nayak1
1Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

Keywords: MR Fingerprinting, MR Fingerprinting, Magnetization transfer effect

Motivation: MT effects influence MRF T1 and T2 quantifications and are stronger at lower field strength.

Goal(s): To evaluate the impact of EPGx dictionary generation on relaxometry performance for 0.55T FISP MRF.

Approach: We applied the EPG-X formalism with a two-pool model which incorporates MT parameters for dictionary simulation for 0.55T FISP MRF and covered a range of realistic MT parameters values. We applied the approach on 4 healthy subjects.

Results: Use of EPGx reduced T2 bias (compared to single-echo spin echo) by 25% at a cost of 80% worse precision.

Impact: Simulating dictionary using the EPG-X formalism with a two-pool model can partially mitigate MT effects and may reduce T2 bias.

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