Keywords: MR Fingerprinting, MR Fingerprinting, Quantitative Susceptibility Mapping
Motivation: To rapidly obtain MRF-based multiparametric quantitative maps in the breast.
Goal(s): To explore the feasibility of using PS-DRONE and an EPI-MRF sequence in breast imaging to simultaneously quantify T1, T2, PD, B1, phase, and QSM maps.
Approach: MRF data were acquired at 3T. Tissue parameters were reconstructed using PS-DRONE, including QSM maps computed from the estimated phase.
Results: Bilateral breast T1, T2, PD, B1 and phase (for QSM analysis) maps were obtained using PS-DRONE and an EPI-MRF sequence. Scan time was 2 minutes and 30 seconds. Parameter reconstruction time was one second. Maps presented differences between the two breasts consistent with diffusion images.
Impact: Comprehensive quantitative T1, T2, PD, B1 and phase (QSM) bilateral breast imaging in under 2.5 minutes can potentially improve the detection and characterization of breast cancer and treatment response in a clinical setting without the use of a contrast agent.
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