Keywords: MR Fingerprinting, MR Fingerprinting, Cardiac MRI, Quantitative MRI, Sequence Design, Contrast Mechanisms
Motivation: Quantification of T1, T2, and T1ρ may provide insight into myocardial fibrosis without the need for gadolinium-based contrast agents.
Goal(s): This study seeks to present and validate a rapid, single breath-hold cMRF approach for simultaneously mapping T1, T2, and T1ρ.
Approach: A cardiac-gated MRF sequence was designed to measure T1, T2, and T1ρ and was tested in simulation, phantom, and six healthy subjects.
Results: The proposed T1/T2/T1ρ cMRF technique yielded accurate high-resolution T1, T2, and T1ρ maps in simulation, phantom, and in vivo.
Impact: Cardiac Magnetic Resonance Fingerprinting can be used to quickly, accurately, and simultaneously map T1, T2, and T1ρ, and has the potential to quickly probe myocardial fibrosis without contrast.
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