Abstract #3589

Case studies evaluating the enhanced visualization and characterization of brain tumor using multi-contrast MRI at 7T

Jiaen Liu^1,2, Yujia Huang¹, Kimberly Chan¹, Mahrshi Jani¹, Yeison Rodriguez¹, Binu Thomas¹, Ivan Dimitrov^1,3, Elizabeth Maher⁴, Toral Patel⁵, and Anke Henning¹

¹Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ²Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ³Philips Healthcare, Cambridge, MA, United States, ⁴Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, ⁵Neurological Surgery, UT Southwestern Medical Center, Dallas, TX, United States

Synopsis

Keywords: Tumors (Post-Treatment), Tumor, High-Field MRI, Multi-contrast

Motivation: Multi-contrast MRI at 7T can potentially lead to enhanced detection and characterization of brain tumor with unpresented sensitivity and specificity.

Goal(s): To evaluate the improvement in tumor boundary, vasculature and hemorrhage detection using a set of complementary MRI sequences at 3T and 7T.

Approach: Five brain tumor patients were scanned with multi-contrast MRI protocols at 7T and 3T. All 7T protocols were implemented with submillimeter resolution in similar scan time as the 3T methods.

Results: At 7T, high image quality was observed in all the protocols because of high contrast and resolution. This led to improved detection of tumor boundary, vasculature, and hemorrhage.

Impact: Multi-contrast ultrahigh field MRI has the potential to non-invasively detect brain tumor in the early stage, provide precise tumor delineation, and visualize tumor-specific processes not seen on conventional MRI.

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