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Abstract #3633

AutoML Radiomics-Based Classification of Patients with Renal Cell Carcinoma Using Non-Contrast Enhanced Magnetic Resonance Imaging

Ming-Cheng Liu1,2, Yen-Ting Lin1, Siu-Wan Hung1, Pin-Sian Lyu3, Yu-zhen Hsieh3, Tzu-Yu Chiu3, and Yi-Jui Liu3
1Department of Radiology, Taichung Veterans General Hospital, Taiwan, Taichung, Taiwan, Taiwan, 2Ph.D. Program of Electrical and Communications Engineering, Feng Chia University, Taichung, Taiwan, taichung, Taiwan, 3Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, taichung, Taiwan

Synopsis

Keywords: Kidney, Radiomics

Motivation: Kidney cancer is often diagnosed as either clear cell renal carcinoma (ccRCC) or non-clear cell renal carcinoma (non-ccRCC) to determine treatment recommendations. Additionally, many patients with kidney cancer cannot receive contrast medium due to renal function disorders.

Goal(s): for the distinction of ccRCC from other types of RCC without contrast medium administration

Approach: A model using automated machine learning (AutoML) based on radiomics features

Results: Our results indicate that the best model from the AutoML process demonstrated a mean sensitivity of 0.819 and a mean specificity of 0.729 in distinguishing between ccRCC and non-ccRCC.

Impact: To demonstrated that the TPOP-radiomics-based classification model can effectively discriminate between ccRCC and non-ccRCC using MRI without the need for contrast medium.

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