Abstract #3634

MRI Radiomics Enhances Radiologists' Ability for Characterizing Intestinal Fibrosis in Patients with Crohn's Disease

Mengchen Zhang¹, Yinghou Zeng², Zhuang-nian Fang¹, Yang-di Wang¹, Ruonan Zhang¹, Ziyin Ye³, Qing-hua Cao³, Chen Zhao⁴, Ren Mao⁵, Canhui Sun¹, Zhi-hui Chen⁶, Bingsheng Huang², and Xuehua Li¹

¹Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, ²Shenzhen University, Shenzhen, China, ³Pathology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, ⁴MR Research Collaboration Team, Siemens Healthineers, Guangzhou, China, ⁵Gastroenterology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, ⁶Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China

Synopsis

Keywords: Digestive, Radiomics, Crohn’s disease; Fibrosis; MR Enterography

Motivation: Fibrostenosis is a severe complication of Crohn's disease that significantly impacts patients' quality of life. Currently, there are no effective medical interventions for severe intestinal fibrosis

Goal(s): We aimed to develop MRI-based radiomic models to improve the diagnostic accuracy of radiologists in characterizing intestinal fibrosis in patients with Crohn’s disease.

Approach: Radiomic models based on different MR sequence combinations were developed and validated in an independent test cohort.

Results: The radiologists’ interpretation aided by MRI-radiomics outperformed visual interpretation in characterizing intestinal fibrosis in Crohn's disease (AUC=0.86-0.93 vs. AUC=0.63-0.77).

Impact: The utilization of MRI-based radiomic models significantly enhances the diagnostic accuracy of radiologists in characterizing intestinal fibrosis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.