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Abstract #3649

Deep Learning for Predicting Prostate Cancer with Gray-Zone Prostate-Specific Antigen Levels to Reduce Unnecessary Biopsies

li zhang1, yi zhu2, shanshan jiang3, kai ai3, and longchao li1
1Shaanxi Provincial People's Hospital, xi'an, China, 2Philips Healthcare, beijing, China, 3Philips Healthcare, xi'an, China

Synopsis

Keywords: Prostate, Machine Learning/Artificial Intelligence

Motivation: Radiologists face challenges in the accurate prediction of prostate cancer (PCa) with gray-zone PSA levels. Deep learning (DL) evaluated PCa with gray-zone PSA levels remains unclear.

Goal(s): The aim of this work was to investigate the comparative performance of DL and radiologists. We trained a 3D DenseNet 121 model for automatic PCa classification with gray-zone PSA levels.

Approach: We trained a 3D DenseNet 121 model for automatic PCa classification with gray-zone PSA levels.

Results: The DL model yielded an AUC of 0.95 (0.85-1.0) for the identification of PCa with gray-zone PSA levels in the test set, significantly improving performance over the inexperienced radiologists.

Impact: The deep learning model yielded an AUC of 0.95 (0.85-1.0) for the identification of PCa with gray-zone PSA levels in the test set, significantly improving performance over the inexperienced radiologists.

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